Publications
Latin American Trans‐ancestry INitiative for OCD genomics (LATINO): Study protocol
2024
James J Crowley, Carolina Cappi, Marcos E Ochoa-Panaifo, Renee M Frederick, Minjee Kook, Andrew D Wiese, Diana Rancourt, Elizabeth G Atkinson, Paola Giusti-Rodriguez, Jacey L Anderberg ; Latin American Trans-ancestry INitiative for OCD genomics (LATINO), Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC); Jonathan S Abramowitz, Victor R Adorno, Cinthia Aguirre, Gustavo S Alves, Gilberto S Alves, NaEshia Ancalade, Alejandro A Arellano Espinosa, Paul D Arnold, Daphne M Ayton, Izabela G Barbosa, Laura Marcela Barón Castano, Cynthia N Barrera, María Belén Prieto, María Celeste Berardo, Dayan Berrones, John R Best, Tim B Bigdeli, Christie L Burton, Jennifer L Callahan, Maria Cecília B Carneiro, Sandra L Cepeda, Evelyn Chazelle, Jessica M Chire, Macarena Churruca Munoz, Pamela Claisse Quiroz, Journa Cobite, Jonathan S Comer, Daniel L Costa, Jennifer Crosbie, Victor O Cruz, Guillermo Dager, Luisa F Daza, Anabel de la Rosa-Gómez, Daniela Del Río, Fernanda Z Delage, Carolina B Dreher, Lucila Fay, Tomas Fazio, Ygor A Ferrão, Gabriela M Ferreira, Edith G Figueroa, Leonardo F Fontenelle, Diego A Forero, Daniele Th Fragoso, Bharathi S Gadad, Sheldon R Garrison, Andres González, Laura D Gonzalez, Marco A González, Polaris Gonzalez-Barrios, Wayne Goodman, Jerry Guintivano, Daniel G Guttfreund, Andrew G Guzick, Matthew W Halvorsen, Joseph D Hovey, Reinhard Janssen-Aguilar, Matias Jensen, Alexandra Z Jimenez Reynolds, Joali Alexandra Juárez Lujambio, Nasim Khalfe, Madison A Knutsen, Caleb Lack, Nuria Lanzagorta, Monicke O Lima, Melanie O Longhurst, David A Lozada Martinez, Elba S Luna, Andrea H Marques, Molly Martinez, Maria de Los Angeles Matos, Caitlyn E Maye, Joseph F McGuire, Gabriela Menezes, Charlene Minaya, Tomás Miño, Sara M Mithani, Circe Montes de Oca, Alonso Morales-Rivero, Maria E Moreira-de-Oliveira, Olivia J Morris, Sandra I Muñoz, Zainab Naqqash, Ambar A Núñez Bracho, Belinda E Núñez Bracho, Maria Corina Ochoa Rojas, Luis A Olavarria Castaman, Iliana Ortega, Darpan I Patel, Ainsley K Patrick, Mariel Paz Y Mino, Jose L Perales Orellana, Bárbara Perdigão Stumpf, Tamara Peregrina, Tania Pérez Duarte, Kelly L Piacsek, Maritza Placencia, Lucas C Quarantini, Yana Quarantini-Alvim, Renato T Ramos, Iaroslava C Ramos, Vanessa R Ramos, Kesley A Ramsey, Elise V Ray, Margaret A Richter, Bradley C Riemann, Juan C Rivas , Maria C Rosario, Camilo J Ruggero, Angel A Ruiz-Chow, Alejandra Ruiz-Velasco, Aline S Sampaio , Leonardo C Saraiva, Russell J Schachar, Sophie C Schneider, Ethan J Schweissing, Laura D Seligman, Roseli G Shavitt, Keaton J Soileau, S Evelyn Stewart , Shaina B Storch, Emily R Strouphauer, Kiara R Timpano, Beatriz Treviño-de la Garza, Javier Vargas-Medrano, María I Vásquez, Guadalupe Vidal Martinez, Saira A Weinzimmer, Mauricio A Yanez, Gwyneth Zai, Lina M Zapata-Restrepo, Luz M Zappa, Raquel M Zepeda-Burgos, Anthony W Zoghbi, Euripedes C Miguel, Carolyn I Rodriguez, Mayra C Martinez Mallen, Pablo R Moya, Tania Borda, María Beatriz Moyano, Manuel Mattheisen, Stacey Pereira, Gabriel Lázaro-Muñoz, Karen G Martinez-Gonzalez, Michele T Pato, Humberto Nicolini, Eric A Storch
A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals
2024
Mariela V Jennings, José Jaime Martínez-Magaña, Natasia S Courchesne-Krak, Renata B Cupertino, Laura Vilar-Ribó, Sevim B Bianchi, Alexander S Hatoum, Elizabeth G Atkinson, Paola Giusti-Rodriguez, Janitza L Montalvo-Ortiz, Joel Gelernter, María Soler Artigas, Stella Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K Bell, Jessica Bielenberg, Katarzyna Bryc, Emily Bullis, Daniella Coker, Gabriel Cuellar Partida, Devika Dhamija, Sayantan Das, Sarah L Elson, Nicholas Eriksson, Teresa Filshtein, Alison Fitch, Kipper Fletez-Brant, Pierre Fontanillas, Will Freyman, Julie M Granka, Karl Heilbron, Alejandro Hernandez, Barry Hicks, David A Hinds, Ethan M Jewett, Yunxuan Jiang, Katelyn Kukar, Alan Kwong, Keng-Han Lin, Bianca A Llamas, Maya Lowe, Jey C McCreight, Matthew H McIntyre, Steven J Micheletti, Meghan E Moreno, Priyanka Nandakumar, Dominique T Nguyen, Elizabeth S Noblin, Jared O'Connell, Aaron A Petrakovitz, G David Poznik, Alexandra Reynoso, Morgan Schumacher, Anjali J Shastri, Janie F Shelton, Jingchunzi Shi, Suyash Shringarpure, Qiaojuan Jane Su, Susana A Tat, Christophe Toukam Tchakouté, Vinh Tran, Joyce Y Tung, Xin Wang, Wei Wang, Catherine H Weldon, Peter Wilton, Corinna D Wong, Howard J Edenberg, Abraham A Palmer, Sandra Sanchez-Roige
Latino OCD: Strategies to Improve Equity in Psychiatric Genetic Studies
2023
Paola Giusti-Rodriguez, Jacey L Anderberg, Olivia Morris, Renee M Frederick, Carolina Cappi, Matthew Halvorsen, Gabriel Lazaro-Munoz, Karen Martinez-Gonzalez, Manuel Mattheisen, Pablo Moya, Humberto Nicolini, Marcos Ochoa-Panaifo, Michele Pato, Andrew D Wiese, James J Crowley, Eric A Storch
F50. Integrative analysis of transcriptome and proteome-wide association study identifies novel genes implicated in Tourette's syndrome
2023
Sudhanshu Shekhar, Apostolia Topaloudi, Dongmei Yu, Paola Giusti-Rodriguez, Matthew Halvorsen, Nora Strom, Pritesh Jain, Tyne Miller-Fleming, Lea Davis, Manuel Mattheisen, James Crowley, Jeremiah Scharf, Carol Mathews, Peristera Paschou
21. Advancing the understanding of depression genetics: An introduction to the major depression working group of the Latin American Genomics Consortium.
2023
Nadia Corral-Frias, Diana Nunez, Vanessa Ota, Jasmine Cárcamo, Cierra Machado, Luis Carlos Hernandez Amaya, María Marcela Velásquez Toledo, Sheila Nagamatsu, Erin Dunn, Bianca Torres-Hernández, Claudia Lattig, Paola Giusti-Rodriguez, Janitza Montalvo-Ortiz, Roseann Peterson, LAGC MDD Working Group
T50. Analyzing large-scale Tourette syndrome whole-exome sequencing data reveals a significant contribution of de novo mutations
2023
Lingyu Zhan, Dongmei Yu, Laura Domenech-Salgado, Franjo Ivankovic, Paola Giusti-Rodriguez, Maria Niarchou, Lea K Davis, Carol A Mathews, Jeremiah M Scharf, Roel A Ophoff
Importance of including individuals of Latin American ancestry in genetic studies of feeding and eating disorders
2023
José Murgueito, José Jaime Martínez-Magaña, Eva Trujillo-Chi Vacuan, Shantal Anid Cortes-Morales, Emilio J Compte, Eric A Storch, Beatriz Elena Camarena, Carolina Muniz Carvahlo, Roseann E Peterson, Sintia Iole Belangero, Janitza L Montalvo-Ortiz, Elizabeth Atkinson, Paola Giusti-Rodríguez, Cynthia M Bulik, Latin American Genomics Consortium
Author Correction: Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia
2022
Matthew Halvorsen, Ruth Huh, Nikolay Oskolkov, Jia Wen, Sergiu Netotea, Paola Giusti-Rodriguez, Robert Karlsson, Julien Bryois, Björn Nystedt, Adam Ameur, Anna K Kähler, NaEshia Ancalade, Martilias Farrell, James J Crowley, Yun Li, Patrik K E Magnusson, Ulf Gyllensten, Christina M Hultman, Patrick F Sullivan, Jin P Szatkiewicz
Gene expression changes following chronic antipsychotic exposure in single cells from mouse striatum
2022
THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data
2022
Bayesian modeling of skewed X inactivation in genetically diverse mice identifies a novel Xce allele associated with copy number changes.
2021
Antipsychotic Behavioral Phenotypes in the Mouse Collaborative Cross Recombinant Inbred Inter-Crosses (RIX).
2020
Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases.
2020
Leina Lu, Xiaoxiao Liu, Wei-Kai Huang, Paola Giusti-Rodríguez, Jian Cui, Shanshan Zhang, Wanying Xu, Zhexing Wen, Shufeng Ma, Jonathan D Rosen, Zheng Xu, Cynthia F Bartels, Riki Kawaguchi, Ming Hu, Peter C Scacheri, Zhili Rong, Yun Li, Patrick F Sullivan, Hongjun Song, Guo-Li Ming, Yan Li, Fulai Jin
Correction: Common-variant associations with fragile X syndrome.
2020
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia
2020
Matthew Halvorsen, Ruth Huh, Nikolay Oskolkov, Jia Wen, Sergiu Netotea, Paola Giusti-Rodriguez, Robert Karlsson, Julien Bryois, Björn Nystedt, Adam Ameur, Anna K Kähler, NaEshia Ancalade, Martilias Farrell, James J Crowley, Yun Li, Patrik K E Magnusson, Ulf Gyllensten, Christina M Hultman, Patrick F Sullivan, Jin P Szatkiewicz
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
2019
Non-coding variability at the APOE locus contributes to the Alzheimer's risk
2019
Common-variant associations with fragile X syndrome.
2019
Legal and ethical implications of CRISPR applications in psychiatry
2019
Integrative functional genomic analysis of human brain development and neuropsychiatric risks
2018
Transcriptome and epigenome landscape of human cortical development modeled in organoids.
2018
Comparative genomic evidence for the involvement of schizophrenia risk genes in antipsychotic effects.
2018
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.
2018
Julien Bryois, Melanie E Garrett, Lingyun Song, Alexias Safi, Paola Giusti-Rodriguez, Graham D Johnson, Annie W Shieh, Alfonso Buil, John F Fullard, Panos Roussos, Pamela Sklar, Schahram Akbarian, Vahram Haroutunian, Craig A Stockmeier, Gregory A Wray, Kevin P White, Chunyu Liu, Timothy E Reddy, Allison Ashley-Koch, Patrick F Sullivan, Gregory E Crawford
Genetic identification of brain cell types underlying schizophrenia
2018
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
2018
Genomes of the Mouse Collaborative Cross.
2017
Anuj Srivastava, Andrew P Morgan, Maya L Najarian, Vishal Kumar Sarsani, J Sebastian Sigmon, John R Shorter, Anwica Kashfeen, Rachel C McMullan, Lucy H Williams, Paola Giusti-Rodríguez, Martin T Ferris, Patrick Sullivan, Pablo Hock, Darla R Miller, Timothy A Bell, Leonard McMillan, Gary A Churchill, Fernando Pardo-Manuel de Villena
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
2017
Russell L McLaughlin, Dick Schijven, Wouter van Rheenen, Kristel R van Eijk, Margaret O'Brien, René S Kahn, Roel A Ophoff, An Goris, Daniel G Bradley, Ammar Al-Chalabi, Leonard H van den Berg, Jurjen J Luykx, Orla Hardiman, Jan H Veldink, Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
2017
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
2016
Barbara Franke, Jason L Stein, Stephan Ripke, Verneri Anttila, Derrek P Hibar, Kimm J E van Hulzen, Alejandro Arias-Vasquez, Jordan W Smoller, Thomas E Nichols, Michael C Neale, Andrew M McIntosh, Phil Lee, Francis J McMahon, Andreas Meyer-Lindenberg, Manuel Mattheisen, Ole A Andreassen, Oliver Gruber, Perminder S Sachdev, Roberto Roiz-Santiañez, Andrew J Saykin, Stefan Ehrlich, Karen A Mather, Jessica A Turner, Emanuel Schwarz, Anbupalam Thalamuthu, Yin Yao Shugart, Yvonne Yw Ho, Nicholas G Martin, Margaret J Wright, Schizophrenia Working Group of the Psychiatric Genomics Consortium; ENIGMA Consortium; Michael C O'Donovan, Paul M Thompson, Benjamin M Neale, Sarah E Medland, Patrick F Sullivan
Schizophrenia risk from complex variation of complement component 4.
2016
Aswin Sekar, Allison R Bialas, Heather de Rivera, Avery Davis, Timothy R Hammond, Nolan Kamitaki, Katherine Tooley, Jessy Presumey, Matthew Baum, Vanessa Van Doren, Giulio Genovese, Samuel A Rose, Robert E Handsaker, Schizophrenia Working Group of the Psychiatric Genomics Consortium; Mark J Daly, Michael C Carroll, Beth Stevens, Steven A McCarroll
The Mouse Universal Genotyping Array: From Substrains to Subspecies
2015
Andrew P Morgan, Chen-Ping Fu, Chia-Yu Kao, Catherine E Welsh, John P Didion, Liran Yadgary, Leeanna Hyacinth, Martin T Ferris, Timothy A Bell, Darla R Miller, Paola Giusti-Rodriguez, Randal J Nonneman, Kevin D Cook, Jason K Whitmire, Lisa E Gralinski, Mark Keller, Alan D Attie, Gary A Churchill, Petko Petkov, Patrick F Sullivan, Jennifer R Brennan, Leonard McMillan, Fernando Pardo-Manuel de Villena
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
2015
A meta-analysis of gene expression quantitative trait loci in brain.
2014
Biological insights from 108 schizophrenia-associated genetic loci.
January 25, 2025
Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment.
2014
The genomics of schizophrenia: update and implications.
2013
Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).
2011
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.
2008